C-Bio-Tech performs sample treatment by capture and concentration of microorganisms, establishing a unique globally applicable approach and having secured intellectual property to operate freely in the market. Sensitivity and specificity of current detection/identification methods is limited by the end-point detection system used in the diagnostic workflow. As a result, a negative diagnostic signal does not necessarily mean the sample is devoid of dangerous pathogens. This is critical for agricultural products (veterinary and crop) as well as for blood product safety while minute quantities of sample-borne pathogens can amplify and increase the risk over time. Our technology addresses this important shortcoming in the current system.
C-Bio-Tech circumvents the enormous challenge by going behind any traditional baseline of pathogen detection, while based on an activated human scavenger protein, so called Apo-lipoprotein-H or ApoHa (also known as beta2 Glycoprotein 1, B2GP1), which:
- Is a innate immunity component with a role of protein scavenger
- Regulates blood coagulation
- Stops the migration of endothelial cells
- Recognizes and binds with high affinity a variety of pathogen components (proteins, phospholipids, myristoiled or palmitoiled groups, etc.).
- Binds specifically with pernicious microorganisms (viruses, bacteria - spores, fungi parasites, prions).
C-Bio-tech is a fully validated core platform technology that has been applied for multiple disease diagnostics with excellent outcomes. Our intellectual property (including trade secrets and patents) provides freedom to operate for applications in the human or veterinary zoonotic disease detection space.
C-Bio-Tech is a straightforward, fast and low-cost method that can be used in any conventional laboratory. ApoH protein can bind to many microorganisms such as viruses, bacteria and parasites improving any diagnostic tests for human health, animal care and food hygiene and security as well as potentially for industrial and space security processes.